Welcome to the Meyerholz Lab
Dr. David Meyerholz has a rich history of leading and collaborating on multidisciplinary scientific teams from medical/veterinary/commercial institutions. As a veterinary pathologist, he is skilled in comparative pathology and translational medicine with proven experience as a leader, mentor and administrator (e.g. Division, cores). His professional background includes: DVM and PhD degrees; dual board certifications; and an extensive portfolio of scientific publications. Dr. Meyerholz’s lab has several areas of research and expertise:
(See Dr. Meyerholz's complete work and bibliography)
Cystic Fibrosis (CF) and Lung Disease
Lung airway disease is an important clinical feature in people with CF. The Meyerholz Lab studies natural disease history in CF airways to help define its early pathogenesis. His studies aim to identity tissue biomarkers and evaluate novel treatments/therapies. Dr. Meyerholz is experienced in analysis of CF tissues in humans as well as animal models (pig, ferret, mouse) and in vitro studies. His lab also studies lung diseases from other causes such as environmental (COPD, developmental) and infectious (e.g. MERS-CoV) etiologies to better understand host defenses, immunology and pathology in the respiratory tract.
Comparative Pathology
Translational medicine is founded on knowledge accrued from basic science to clinical studies; this research often involves animal models. As a veterinary pathologist, Dr. Meyerholz has several perspectives / skills as a veterinarian, scientist and pathologist to help complement and enhance the interdisciplinary scientific team. He has published on best practices in comparative pathology and serves as an educator at workshops and scientific meetings on valid approaches in multidisciplinary research.
Reproducible Approaches in Tissue Evaluation
Dr. Meyerholz is a recognized leader and educator on the standards and approaches for maximizing the reproducibility and impact of tissue studies in scientific research. His investigations have emphasized the importance of reproducibility and validity in scientific investigations. Dr. Meyerholz’s studies advocate reproducibility and quality in tissue examination, interpretation and scoring (semiquantitative and quantitative) techniques.